(±)-(2R*)-2,5,7,8-tetramethyl-2-[(4R*,8R*)-4,8,12-trimethyltridecyl]-6-chromanyl retinoate
Tretinoin Tocoferil
CAS: 40516-48-1
Molecular Formula: C49H76O3
(±)-(2R*)-2,5,7,8-tetramethyl-2-[(4R*,8R*)-4,8,12-trimethyltridecyl]-6-chromanyl retinoate - Names and Identifiers
(±)-(2R*)-2,5,7,8-tetramethyl-2-[(4R*,8R*)-4,8,12-trimethyltridecyl]-6-chromanyl retinoate - Physico-chemical Properties
| Molecular Formula | C49H76O3 |
| Molar Mass | 713.13 |
| Density | 0.959g/cm3 |
| Boling Point | 761.3°C at 760 mmHg |
| Flash Point | 339.8°C |
| Vapor Presure | 4.49E-23mmHg at 25°C |
| Refractive Index | 1.523 |
(±)-(2R*)-2,5,7,8-tetramethyl-2-[(4R*,8R*)-4,8,12-trimethyltridecyl]-6-chromanyl retinoate - Risk and Safety
| Toxicity | LD50 in mice (mg/kg): >1000 i.v.; >2000 orally (Fukawa, 1975) |
(±)-(2R*)-2,5,7,8-tetramethyl-2-[(4R*,8R*)-4,8,12-trimethyltridecyl]-6-chromanyl retinoate - Introduction
Tretinoin Tocoferil is a derivative of tretinoin, also known as Tretinoin Tocoferil. The following is a description of its nature, use, preparation and safety information:
Nature:
Tretinoin Tocoferil is a yellow crystalline powder, soluble in some organic solvents such as ethanol and dimethyl sulfoxide. It is unstable under light and easily oxidized.
Use:
Tretinoin Tocoferil are primarily used to treat skin problems such as acne and wrinkles. It has the effect of promoting cell growth and skin cell renewal, is able to improve the texture and color of the skin. In addition, Tretinoin Tocoferil can also be used to treat other skin lesions, such as melanosis and photoaging.
Preparation Method:
The preparation of Tretinoin Tocoferil is mainly carried out by synthetic methods. A common synthetic route is the reaction of retinoic acid with tocopheryl esters to produce Tretinoin Tocoferil.
Safety Information:
Note the following when using Tretinoin Tocoferil:
1. Tretinoin Tocoferil can only be used externally, not orally, to avoid stray into the eyes and mouth.
2. The use of Tretinoin Tocoferil may cause skin irritation and dryness, especially at the beginning of use. The frequency and concentration of use should be gradually increased to reduce discomfort.
3. pregnant women disable Tretinoin Tocoferil, because it may have adverse effects on the fetus.
4. After using Tretinoin Tocoferil, avoid excessive exposure to the sun, because it will increase the sensitivity to ultraviolet rays and cause skin sunburn.
5. During the use of Tretinoin Tocoferil, avoid using other irritating cosmetics or drugs at the same time to avoid adverse reactions.
Nature:
Tretinoin Tocoferil is a yellow crystalline powder, soluble in some organic solvents such as ethanol and dimethyl sulfoxide. It is unstable under light and easily oxidized.
Use:
Tretinoin Tocoferil are primarily used to treat skin problems such as acne and wrinkles. It has the effect of promoting cell growth and skin cell renewal, is able to improve the texture and color of the skin. In addition, Tretinoin Tocoferil can also be used to treat other skin lesions, such as melanosis and photoaging.
Preparation Method:
The preparation of Tretinoin Tocoferil is mainly carried out by synthetic methods. A common synthetic route is the reaction of retinoic acid with tocopheryl esters to produce Tretinoin Tocoferil.
Safety Information:
Note the following when using Tretinoin Tocoferil:
1. Tretinoin Tocoferil can only be used externally, not orally, to avoid stray into the eyes and mouth.
2. The use of Tretinoin Tocoferil may cause skin irritation and dryness, especially at the beginning of use. The frequency and concentration of use should be gradually increased to reduce discomfort.
3. pregnant women disable Tretinoin Tocoferil, because it may have adverse effects on the fetus.
4. After using Tretinoin Tocoferil, avoid excessive exposure to the sun, because it will increase the sensitivity to ultraviolet rays and cause skin sunburn.
5. During the use of Tretinoin Tocoferil, avoid using other irritating cosmetics or drugs at the same time to avoid adverse reactions.
Last Update：2024-04-09 20:52:54
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